Lumbrokinase For Circulatory Health USA 80mg x 48 Caps Clinically Proven to Prevent and Disperse Blood Clots and Aid in Stroke Prevention

For CIRCULATORY HEALTH

Spruce Nutrition Lumbrokinase is an enzyme derived from Lumbricus rubellus, a species of earthworm. It is classified as a fibrinolytic enzyme (a substance that promotes the breakdown of fibrinogen, a protein involved in the formulation of blood clots). According to some studies, supplementation of lumbrokinase can prevent and disperse blood clots and prevent strokes.*

WHO NEEDS:

• Those who need or wish to improve smooth blood circulation
• If you consume instant food frequently
• If you are under a lot of stress from overwork
• For those who want to live an active life
• If you have irregular eating habits
• If you wish to take vitamins & minerals for general well being

BENEFITS & FUNCTIONS

• Support a healthier blood state by aiding coagulation & fibrinolysis balance in the body
• Improves hypercoagulation (“a thicker blood state”) by supporting, regulating & balancing the coagulation system
• Effective for acute, sub-acute & chronic conditions with thicker blood & poor circulation

QUALITY GUARANTEED

NO added sugar (sucrose, fructose, lactose), salt, (sodium chloride) yeast, wheat, gluten, or milk.

NO preservatives, artificial colors, or artificial flavors

GUARANTEED for purity, freshness, and labeled potency

DIRECTIONS：

1 to 2 CAPS DAILY, or as recommended by a health care professional.

ONE HOUR before a meal

or

TWO HOURS after a meal

OTHER INGREDIENTS:

Gelatin, magnesium stearate, silicon dioxide

STORAGE:

Keep out of reach of children. Store in a cool, dry place with the lid tightly closed.

CAUTION:

Pregnant and breastfeeding women and people with coagulopathy, heart disease, or hypertension should consult the doctor before taking this product. Discontinue use immediately if any adverse reactions occur. Please take the product at least half an hour after taking other medicines.

CLINICAL STUDY

A study in rats was conducted to evaluate the effects of lumbrokinase-containing earthworm powder on induced thrombotic blood clots in vivo. The powder was administered orally to rats and its fibrinolytic and antithrombotic effects were investigated. The fibrinolytic activity of plasma was increased to two-folds of the control at a dose of 0.5 g/kg/day and five times with 1 g/kg/day after 4-day administration. The antithrombotic effect was studied in an arterio-venous shunt model of rats. The weight of the blood clots decreased significantly from 43.2 mg to 32.4 mg at a dose of 0.5 g/kg/day after 8-day treatment. These results support that lumbrokinase-containing earthworm powder is valuable in maintaining healthy blood flow.*17

A clinical study, involving 51 participants, was conducted to investigate the anticoagulation effect and fibrinolytic activity of lumbrokinase in humans. These participants were randomly divided into treatment group (n = 31) and control group (n = 20). Among other parameters, prothrombin time (PT), fibrinogen content, tissue plasminogen activator (t-PA) activity, plasminogen activator inhibitor (PAI) activity, and D-dimer level were assayed. In the treatment group, t-PA activity and D-dimer level increased, while the content of fibrinogen decreased significantly. There were no significant changes of PT and PAI activity in both groups. The researchers concluded that lumbrokinase is beneficial in lowering fibrinogen levels*. The effect of lumbrokinase may be related to the inhibition of intrinsic coagulation pathway and the activation of fibrinolysis via an increase of t-PA activity.6

In a study conducted at Beijing Tongren Hospital, participants with high levels of fibrinogen were given lumbrokinase tablets to take orally every day for three weeks. Serum fibrinogen levels were examined before and after treatment. In comparison with the control group, serum fibrinogen in the lumbrokinase group significantly decreased two weeks after treatment. These results demonstrated lumbrokinase may lower blood viscosity. Moreover, there were no side effects related to the intake of lumbrokinase.1

DISCLAIMER:

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.